Description
Product Characteristics: A127 antibody, DNA directed RNA polymerase I 135 kDa polypeptide antibody, DNA directed RNA polymerase I antibody, DNA directed RNA polymerase I subunit RPA2 antibody, DNA-directed RNA polymerase I 135 kDa polypeptide antibody, DNA-directed RNA polymerase I subunit rpa2 antibody, FLJ10816 antibody, FLJ21921 antibody, MGC131780 antibody, OTTHUMP00000161989 antibody, OTTHUMP00000203643 antibody, OTTHUMP00000203645 antibody, POLR 1B antibody, polr1b antibody, Polymerase (RNA) I polypeptide B 128 kDa antibody, Polymerase (RNA) I polypeptide B antibody, RNA polymerase I polypeptide B antibody, RNA polymerase I subunit 2 antibody, RPA 135 antibody, RPA116 antibody, RPA135 antibody, RPA2 antibody, RPA2_HUMAN antibody, Rpo1 2 antibody
Target Information: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]